Mesotherapy involves injecting small amounts of selected products into the superficial or middle layers of the skin using very fine needles. Depending on the treatment, these products may contain hyaluronic acid, amino acids, vitamins, minerals, or other active ingredients.
Mesotherapy does not refer to a single medicine or standardised product. The ingredients, concentration, injection depth, and intended purpose can vary considerably. Its potential benefits and risks must therefore be assessed according to the exact product used and the injection technique.
Following a dermatological assessment, mesotherapy may be considered for:
Supporting skin hydration and improving a dull appearance
Addressing selected changes in skin texture
Softening the appearance of fine lines
Supporting the treatment of certain types of hair loss
Treating selected areas of the face and neck with suitable products
Mesotherapy is not a universal treatment for every wrinkle, pigmentation concern, or type of hair loss. The purpose of treatment and the exact product being used should always be clearly defined.
Depending on the product used, facial mesotherapy may aim to support skin hydration, superficial texture, and overall appearance.
It does not work in the same way as botulinum toxin, dermal fillers, or laser treatments and should not be considered a substitute for these procedures.
The scientific evidence supporting facial mesotherapy varies according to the ingredients used. Evidence is particularly limited and inconsistent for non-standardised multivitamin mixtures.
Before considering mesotherapy for hair loss, the underlying cause must be identified. Androgenetic alopecia, telogen effluvium, alopecia areata, vitamin or iron deficiencies, and hormonal disorders require different approaches.
Scalp mesotherapy may be considered as a supportive option for selected patients. However, it cannot be guaranteed to stop hair loss or stimulate new hair growth.
Although some studies have reported positive findings, stronger evidence is still needed because the products and treatment protocols used in scalp mesotherapy are not standardised.
Dark circles, hollows, and under-eye bags can have different causes, and not every under-eye concern is suitable for mesotherapy.
Patients with prominent fat pads, structural hollows, or visible blood vessels may require a different treatment approach.
Because the eye area is anatomically delicate, the product, injection depth, skin characteristics, and the patient’s tendency to develop swelling must be assessed carefully.
Before the procedure, the treatment area is cleansed. A topical anaesthetic cream may be applied if appropriate. The selected product is then injected into the skin in small amounts at carefully planned intervals.
The length of the procedure depends on the size of the treatment area. Small raised bumps, redness, tenderness, swelling, or bruising may occur afterwards. Mesotherapy therefore cannot be guaranteed to have no effect on work or social activities.
The number of sessions depends on the product used, the treatment goal, the area being treated, and the patient’s response.
There is no standard “three-to-six-session course” that is suitable for everyone. Some products may require an initial series of treatments followed by maintenance sessions.
The interval between sessions and the need for maintenance treatment should be determined individually.
Possible side effects and complications include:
Pain, redness, and tenderness
Swelling and bruising
Itching or allergic reactions
Temporary bumps at the injection sites
Pigmentation changes
Infection
Nodules or granulomas
Tissue damage or scarring in rare cases
The lack of standardisation among mesotherapy products and mixtures can make the risk of complications more difficult to assess. The product’s ingredients, manufacturer, approval status, and intended use should therefore be known before treatment.
Treatment may need to be postponed if there is an active infection or open wound in the treatment area.
Pregnancy, breastfeeding, bleeding disorders, immune system conditions, a history of severe allergic reactions, and the use of blood-thinning medication should all be discussed and assessed before the procedure.
At Dr. Armin Müştak’s dermatology practice in Çankaya, Ankara, the patient’s skin or hair concern, medical history, current medications, previous treatments, and expectations are assessed before mesotherapy.
For suitable patients, an individual treatment plan is created after discussing the product’s ingredients, the treatment area, the proposed session schedule, potential benefits, limitations, and possible risks.
Mesotherapy is a technique in which small amounts of selected products are injected into the skin using fine needles. It does not refer to a single product or a fixed formulation. The product, treatment area, and treatment goal are determined after a clinical assessment. Effectiveness and safety depend on the properties of the injected substance and the injection technique.
Facial mesotherapy may be considered for suitable patients to improve skin hydration, texture, and the appearance of fine lines. Studies of certain hyaluronic acid–containing products have shown benefits in these areas. However, results achieved with one product cannot be generalized to all mesotherapy formulations. Significant sagging or volume loss may require other treatments. Results vary depending on the product used and each patient’s skin characteristics.
Facial mesotherapy may be considered for suitable patients to improve skin hydration, texture, and the appearance of fine lines. Studies of certain hyaluronic acid–containing products have shown benefits in these areas. However, results achieved with one product cannot be generalized to all mesotherapy formulations. Significant sagging or volume loss may require other treatments. Results vary depending on the product used and each patient’s skin characteristics.
There is no single number of sessions or treatment interval that applies to everyone. The plan is based on the recommended protocol for the product used, the treatment area, and the response to treatment. Changes in skin quality may be assessed within a few weeks, while scalp treatments require longer follow-up. Effects should not be considered permanent. At follow-up visits, the benefits are evaluated to determine whether further treatment or maintenance sessions are needed.
You may feel stinging, burning, or tenderness during the injections. Redness, small bumps, and bruising may occur afterward. Possible complications include allergic reactions to the injected ingredients, infection, nodule formation, skin discoloration, and scarring. Products with known ingredients that are suitable for injection should be administered by a physician under sterile conditions. Increasing pain, spreading redness, drainage, or persistent swelling requires medical assessment.
Mesotherapy should not be performed if there is an active infection in the treatment area or a known allergy to the product to be used. Patients with bleeding disorders, immune system conditions, or a tendency to develop keloid scars, as well as those taking blood thinners, require further assessment. Cosmetic treatments are generally postponed during pregnancy and breastfeeding. During the consultation, tell your physician about any medications you take, previous injections, and allergies. Do not stop taking prescribed medications without consulting your physician.
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