Hair loss is a common dermatological concern that can affect both men and women at different stages of life. In some cases, it results from a temporary change in the natural hair-growth cycle. In others, it may be linked to genetic predisposition, hormonal changes, immune-related conditions or diseases affecting the scalp.
The pattern, duration and progression of hair loss vary from person to person. Before treatment begins, it is therefore important to identify the type of hair loss and investigate its possible causes. Not every form of hair loss responds to the same medication, supplement or procedure.
Hair loss does not have a single cause. Possible contributing factors include:
Genetic predisposition
Physical or emotional stress
High-fever illnesses and severe infections
Surgery or other physically stressful events
Pregnancy and the postpartum period
Rapid weight loss or inadequate nutrition
Iron deficiency and other nutritional deficiencies
Thyroid disorders
Hormonal changes
Certain medications
Immune-related conditions
Inflammatory or infectious diseases of the scalp
Tight hairstyles that repeatedly pull on the hair
Excessive heat, chemical treatments and traumatic styling practices
Not every possible cause needs to be investigated in every patient. The necessary examinations and tests should be selected according to the individual’s medical history and the findings of the dermatological examination.
Hair loss may be diffuse, affecting the scalp more widely, or localised to specific areas. It can also be classified as non-scarring or scarring, depending on whether the hair follicles have sustained permanent damage.
Androgenetic alopecia is a common form of hair loss associated with genetic and hormonal factors.
In men, it typically causes a receding hairline, thinning at the temples and hair loss at the crown. In women, it more commonly appears as widening of the parting and diffuse thinning across the top of the scalp.
This type of hair loss usually progresses gradually. Early assessment can be helpful when planning treatment intended to preserve existing hair and slow further thinning.
Telogen effluvium is a form of diffuse hair shedding that occurs when a higher-than-normal number of hairs enter the resting and shedding phase of the hair-growth cycle.
It may develop after a high-fever illness, severe infection, surgery, childbirth, significant emotional stress, rapid weight loss, certain medications or nutritional deficiencies. Hair shedding often begins several weeks or months after the triggering event.
Acute telogen effluvium is often temporary. However, persistent shedding may require further investigation for underlying causes or co-existing androgenetic alopecia.
Alopecia areata is an immune-related condition that most commonly causes smooth, round or oval patches of hair loss on the scalp or beard area.
The eyebrows, eyelashes and other areas of body hair may also be affected. Its extent and course vary between individuals. Alopecia areata is not contagious.
In scarring alopecia, inflammation damages the hair follicles and may result in permanent hair loss. Symptoms can include redness, scaling, crusting, burning, itching, pain or tenderness of the scalp.
Early diagnosis is particularly important because hair that has already been lost may not regrow. The main aim of treatment is to control the underlying disease, slow or stop its progression and protect the remaining hair follicles.
Seborrhoeic dermatitis, psoriasis, fungal infections and other inflammatory scalp conditions may be accompanied by hair loss or changes in hair quality.
In these cases, the assessment should include not only the hair itself but also scalp symptoms such as redness, flaking, crusting, sores, itching, burning or tenderness.
During a dermatological assessment, the dermatologist considers when the hair loss began, how long it has continued and whether it affects the scalp diffusely or in clearly defined areas.
The assessment may include:
Hair density and distribution
Hair-shaft thickness
Changes in the parting line
The appearance of the hair follicles
Signs of scalp inflammation or scarring
Changes affecting the eyebrows, eyelashes, beard or body hair
Nail changes
A hair-pull test
Family history of hair loss
Current and recently used medications
Recent illnesses, surgery or periods of significant stress
Dietary habits and weight changes
Menstrual irregularities or other hormonal symptoms in women
Trichoscopy, also known as scalp dermoscopy, allows the hair shafts, follicular openings and scalp structures to be examined in greater detail.
When indicated by the patient’s history and examination findings, tests such as a full blood count, iron studies, thyroid function tests or other relevant laboratory investigations may be requested. The same blood tests are not required for every patient.
A scalp biopsy may occasionally be necessary when the diagnosis remains unclear or scarring alopecia is suspected.
Treatment is selected according to the type and underlying cause of the hair loss, the condition of the scalp and the individual patient’s medical needs.
Losing approximately 50–100 hairs per day is considered part of the normal hair growth cycle. However, the amount may vary depending on how often the hair is washed and brushed, so counting individual hairs alone is not enough to determine whether hair loss is abnormal.
A dermatologic evaluation is recommended if shedding increases noticeably, the part line begins to widen, the hairline recedes, or distinct areas of thinning develop. Assessment should not be delayed if the hair loss is accompanied by scalp redness, scaling, pain, or burning.
Hair loss may result from genetic predisposition, certain medical conditions, nutritional deficiencies, medications, or diseases affecting the scalp. Diffuse shedding may begin approximately 2–3 months after a febrile illness, surgery, childbirth, severe stress, or rapid weight loss. This condition is known as telogen effluvium and is often temporary.
However, not every case of hair loss should be attributed to stress. Pattern hair loss, alopecia areata, and conditions that can cause permanent hair loss require different approaches to diagnosis and treatment.
The evaluation begins with the duration and pattern of hair loss, as well as the patient’s medications, diet, and medical history. A scalp examination, hair pull test, and, when necessary, a magnified examination known as trichoscopy may be performed.
Depending on the findings, blood tests such as a complete blood count, ferritin level, and thyroid function tests may be ordered. Routine vitamin and hormone testing is not necessary for every patient. Hormonal testing may be considered when there are additional signs such as irregular menstrual cycles or increased facial or body hair. In some cases where the diagnosis remains unclear, a scalp biopsy may be required.
Treatment is selected according to the underlying cause of hair loss. For pattern hair loss, topical minoxidil may be recommended, while finasteride may be considered for suitable male patients. Other medications may be evaluated on an individual basis for women.
In temporary forms of hair shedding, addressing the trigger and correcting any identified deficiencies may be sufficient. Alopecia areata and inflammatory scalp disorders require different treatment approaches. Potential side effects and pregnancy plans must be considered; minoxidil and finasteride should not be used during pregnancy. The same treatment is not appropriate for every patient, and results may vary.
Because of the hair growth cycle, treatment results cannot be assessed within just a few weeks. With pattern hair loss, it may take 6–12 months to see a noticeable response. A temporary increase in shedding may occur when minoxidil is first started.
The benefits of treatments for pattern hair loss may gradually be lost after treatment is discontinued, so long-term use may be necessary. With temporary telogen effluvium, shedding usually decreases within a few months, although restoring the hair’s previous density may take longer. Standardized photographs and scalp examinations can be helpful for monitoring progress.
PRP may help improve hair density in selected patients, particularly those with pattern hair loss. However, individual responses vary, and repeated treatment sessions may be necessary. The ingredients and techniques used in hair mesotherapy are not standardized, and evidence regarding its effectiveness and safety is more limited than for established medical treatments.
These procedures should not automatically replace diagnosis-based treatment. Supplements such as iron, zinc, or biotin should be used only when a deficiency or specific medical need has been identified. Taking supplements without a confirmed deficiency does not guarantee hair growth, and unnecessary use may be harmful.
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